The main side effect of doxorubicin is myelosuppression, which causes a decrease in white blood cells, which is related to the dose of doxorubicin, the higher the dose used, the more pronounced the decrease in white blood cells, and also causes a mild thrombocytopenia. Other side effects include skin toxicity, alopecia, nausea, vomiting, diarrhea, oral mucositis, etc. In some cases, there may be drug-induced fever, and in some cases, mild allergic reactions, such as itching, flushing, and rashes may occur, but severe allergic reactions are rare. Side effects of doxorubicin are generally mild, some do not need to be treated, while others can be treated with symptomatic treatment.