Treatment and prevention of carotid artery stenosis

  Cerebral infarction caused by carotid stenosis accounts for about 60% of the incidence of acute cerebral infarction. The risk level can be easily detected and evaluated during routine ultrasound and CTA/MRA examinations of the carotid arteries. Timely detection and proper management of stenoses greater than 80% or with unstable plaques will undoubtedly reduce the chance of cerebral infarction to a great extent.  There is a 60-70% correlation between the severity of carotid stenosis and cardiac coronary stenosis; therefore, in most cases, examination of the severity of carotid plaque can infer cardiac coronary atherosclerosis, thus partially suggesting the need to pay attention to the possibility of coronary artery disease. Carotid artery stenosis can cause cerebral infarction due to embolism caused by the dislodgement of wall clots on the surface of sclerotic plaque or debris on the surface of unstable plaque that enters the brain with blood flow; separation of sclerotic plaque and vessel wall to form a sandwich or very severe stenosis that causes complete blockage of the carotid artery lumen, resulting in massive cerebral infarction; or severe stenosis to form a persistent low blood flow state that causes cerebral ischemia characterized by watershed infarction. The following are some examples.  Therefore, it is not necessary to be nervous when a mild atherosclerotic platelet is found by ultrasound or CTA examination of the neck during physical examination, because the stenosis formed by a stable plaque in the carotid artery does not exceed 70-80%, which generally does not cause significant cerebral ischemia, and it is recommended to apply lipid-lowering and anti-platelet drugs under the guidance of a doctor for long-term conservative treatment. If the stenosis has obviously caused cerebral ischemic symptoms, or if the stenotic plaque has broken down and become unstable, timely medical intervention is a wise choice.  The current treatment for carotid stenosis is intra-arterial stenting and endarterectomy, both of which have achieved positive safety and effectiveness in clinical applications. The advantages of stenting are that it is less painful for the patient and relatively easy to perform; it can be performed on severe stenosis of the entire carotid system; therefore, it has a wide range of indications, especially for elderly patients with uncontrollable hypertension, diabetes mellitus, cardiac or renal insufficiency or various reasons who cannot tolerate surgical procedures. The carotid endarterectomy can completely remove the atherosclerotic plaque in the stenosis and completely unblock the carotid artery; this procedure has been honed for decades and the effect is certain. The advantages of both procedures complement each other and have developed into a routine treatment for cerebral power insufficiency caused by carotid stenosis.