Hiccups and chest pain may be caused by gastroesophageal reflux, gastrointestinal disorders caused by digestive diseases, and diaphragmatic spasms due to various reasons. 1. Gastroesophageal reflux: the acid in the stomach of this group of people may reflux into the esophagus when they burp, which makes the esophagus have a burning pain sensation, that is, it is manifested as hiccups and chest pain. This situation can be treated with acid-suppressing drugs or gastrointestinal power drugs, such as Famotidine, Domperidone, etc. 2. Some digestive diseases may cause gastrointestinal dysfunction, such as chronic gastritis, gastric ulcer, etc., which cause spasm of diaphragm and chest pain when hiccups occur, and it is recommended to go to the hospital for gastroscopy to find out the cause of the disease, and then carry out the corresponding treatment of the underlying disease. 3. Improper diet may cause temporary diaphragmatic spasm, manifested as hiccups accompanied by chest pain, which can be relieved on its own. Medications should be used under the guidance of a doctor and should not be used without authorization.