Children who have had chickenpox are usually not infected a second time. After chickenpox is cured, the child can get long-lasting immunity, so if the child has had chickenpox before, the body will produce protective antibodies, which can prevent the second infection of chickenpox herpes virus. However, the virus can remain latent in the ganglia of the body for a long time, which can lead to herpes zoster if immunity is reduced in adulthood. Instead, it causes a second chickenpox infection. Children with chickenpox infection will present with fever, a blistering rash all over the body, and itchy skin. Infectiousness is relatively strong. However, with aggressive treatment, the prognosis is generally good and treatment can result in lifelong immunity. Once diagnosed, it is important to isolate and treat.