1. The disease has been in basic remission for more than 6 months. 2.Anti-cardiolipin antibody is negative. Positive patients are prone to miscarriage and stillbirth. 3.Take maintenance dose of prednisone below 15mg or no hormone. 4.Pregnancy should be followed up regularly under the observation of a specialist and delivery in an experienced hospital obstetrics department. 5.Since the placenta can oxidize prednisone to the inactive 11-ketone form, it protects the fetus. Therefore prednisone taken by the mother has no effect on the fetus. To prevent deterioration during pregnancy and postpartum, the dose should be increased depending on the condition. The original dose can be restored for stable conditions. 6. Dexamethasone and betamethasone cannot be oxidized by placental enzymes and can affect the fetus, so patients taking such hormones need to be replaced with prednisone. 7. More calcium should be added during pregnancy and lactation, otherwise it will accelerate the osteonecrosis of the patient. 8. The dose of prednisone during breastfeeding should be below 15 mg per day and not more than 30 mg at most. 9. Salicylates, non-steroidal anti-inflammatory drugs, and antimalarial drugs are prohibited for pregnant women. Immunosuppressants should also be discontinued. 10. Pay attention to the protection of ovarian function and use ovarian toxic drugs with caution. 11.Master the timing of pregnancy. 12. Monitor closely and use drugs appropriately.