Blisters on the glans are recommended to undergo relevant tests at the hospital to clarify the cause of blister production for symptomatic treatment. First, if the patient is asked about a history of excessive masturbation, the blisters may be related to overstimulation. It is recommended to stop the overstimulation exercise and keep the area clean and dry. The blisters can disappear on their own after about 3-4 days. Second, if there is a history of unclean sexual contact, consider whether the herpes virus was contracted through sexual intercourse. This is mostly due to herpes simplex virus type 2 infection, which can appear as clusters of blisters. After the diagnosis is confirmed, antiviral treatment is needed, which can be oral acyclovir 400mg/day 3 times for 7-10 days, and topical acyclovir ointment is applied topically a little 3-4 times a day for a week. Third, may also be due to glansitis and local blisters, inflammation further aggravated can become pustules need to be anti-infection treatment. If you are looking for a good deal more than just a little bit of Bactroban ointment 3 times a day, you can also take a cefixime capsule orally twice a day for a week to see if the blisters disappear.