Menkes disease is a rare inborn disease of abnormal copper metabolism. Menkes disease is a rare X-chromosome-linked recessive disorder, in which patients usually have a low concentration of plasma copper blue protein and copper-containing enzymes, while copper absorption in the small intestine is normal. The clinical manifestations of Menkes disease are similar to those of copper deficiency, usually with light skin and hair color, curly hair, and mental retardation, and are usually treated with copper sulfate. If you are diagnosed with Menkes disease or have the above clinical manifestations, it is recommended that you consult a doctor as soon as possible and under the guidance of a professional doctor, in order to avoid delays and serious consequences.