IBS patients with fever is best not to eat ibuprofen, including ibuprofen, including non-steroidal anti-inflammatory drugs are avoided as much as possible, such as aspirin, indomethacin, naproxen, acetaminophen and so on. These drugs antipyretic, analgesic, anti-inflammatory, anti-rheumatic effect is very significant, the most common side effect is to induce and aggravate acute hemorrhagic gastritis and peptic ulcer. Patients with gastroenteritis may be at risk of congestion, edema, erosion and bleeding of the gastrointestinal mucosa, which can be exacerbated if NSAIDs are taken orally. Some patients with gastroenteritis have fever, first give physical cooling, give ice pillows, alcohol baths, etc., also can take oral Xiao Chaihu granules as well as clearing heat and removing toxins oral solution to relieve the symptoms. If the fever does not go down, give indomethacin suppositories to reduce the gastrointestinal irritation caused by direct oral intake. At the same time, patients are advised to eat light, easy to digest, warm and soft food, small meals to promote recovery.