Stomach pain after eating too much at night is mainly caused by indigestion and peptic ulcer. It can be relieved by massaging the abdomen, applying hot compresses, drinking warm water and taking medication. If you eat too much at night, it will increase the burden on the gastrointestinal tract, resulting in indigestion. Patients can help alleviate the symptoms through clockwise massage of the abdomen, placing hot water bags on the abdomen and drinking warm water in moderation. In addition, you can also take drugs to promote digestion, such as gastrointestinal tablets, to promote the digestion and absorption of food, which can effectively reduce stomach pain. If the patient has peptic ulcer, stomach pain will also occur after eating too much. Drugs that inhibit gastric acid and protect the gastric mucosa, such as Esomeprazole magnesium enteric-coated tablets, Omeprazole magnesium enteric-coated tablets, and Aluminum Thiosulphate Chewable Tablets, need to be used to reduce the secretion of gastric acid, and also to promote the healing of the gastric mucosa. Note that the above drugs should be used under the guidance of a doctor, avoid unauthorized use of drugs to avoid adverse effects. If the patient’s symptoms are not improved by the above methods, it is recommended to consult a doctor in a timely manner, improve the relevant examination, clarify the cause of the disease, and symptomatic treatment.