Which is the best vaginal medication depends mainly on the reason for which the medication is needed. If the vaginal medication is needed due to bacterial vaginosis, it can be treated with metronidazole suppositories. If it is due to Candida vaginitis, it is clinically necessary to treat with mycophenolate suppositories. If the infection is due to mycoplasma or chlamydia, it is clinically treated with oral azithromycin or clarithromycin or erythromycin. So the drugs used are different for different vaginal inflammations. In addition, in case of trichomoniasis, clinically you need to use tinidazole suppositories or metronidazole suppositories inserted into the vagina for one week.