The skull is a very important bone in our head, it is the barrier between our brain and the outside world, protecting the normal operation of the tissues in the brain. The skull may be defective for many reasons, such as accidental fall from a height, being hit by a heavy object that easily causes brain damage, or because of the lesion of the skull itself that requires debridement surgery, thus causing the defect of the skull. The skull defect should be repaired in time, but of course, the repair material is very important when repairing the skull. Some repair materials can also cause side effects after the repair, and the most widely used titanium mesh can cause rejection or other side effects in some patients after using it, so patients have to choose the repair hospital and materials carefully and carefully. At present, some hospitals are using a new material for patients to carry out cranial repair, polyether ether ketone material, which is commonly known as peek material is the most ideal repair material recognized by many experts at present, in use since, many cranial repair patients have carried out repair surgery through peek material, and after long-term follow-up found that the basic recovery after surgery is very good. It is recommended that patients use polyether ether ketone (PEEK) material for cranial repair. PEEK material for cranial repair is comparable to autologous cranial bone in terms of thermal insulation, strength hardness, and elasticity, etc. The excellent PEEK material as a cranial repair material can be used with 3D printing technology to perfectly restore the anatomical structure of the cranium and precisely fit the defect area, which is the best choice for cranial repair patients.