Pain in the ankle after standing for a long time is commonly caused by the following reasons: 1, strain of the ankle joint and surrounding soft tissues, patients will show pain, mainly due to long-term standing so that the ligaments around the ankle joint capsule, such as the medial collateral ligament, lateral collateral ligament and synovial membrane have serious strain, patients will have clinical manifestations such as soreness and pain, and the symptoms will disappear soon after rest. 2, suffering from osteoarthritis of the ankle joint, rheumatoid arthritis and rheumatoid arthritis. Rheumatoid arthritis and rheumatoid arthritis are diseases that can lead to structural damage in the joints, such as articular cartilage damage and synovial inflammation. Prolonged standing can irritate the inflamed synovial membrane and damaged articular cartilage, resulting in ankle pain. The degree of pain symptoms can vary significantly, with rheumatoid arthritis and rheumatoid arthritis, the pain symptoms are relatively severe.