It is impossible to accurately determine how long bone tuberculosis medication will relieve pain; the standard course of treatment for bone tuberculosis usually takes one and a half years, and may be longer, up to two years or more, if tuberculosis resistance develops. Bone tuberculosis is a destructive lesion caused by the invasion of tubercle bacilli into the skeletal system, which belongs to the secondary tuberculosis, infected with tubercle bacilli from other parts of the body with the blood or lymphatic circulation colonization to the skeletal and muscular system, caused when the body’s immunity is reduced. Regardless of whether the bone tuberculosis is operated or not, it should be treated with regular, sufficient amount of anti-tuberculosis drugs for the whole course of treatment, and different courses of treatment should be chosen according to the condition, and most of the patients can be clinically cured in about one and a half years, and if there is tuberculosis resistance, the recovery time can be up to two years and above. Commonly used drugs such as isoniazid, rifampicin and so on. It is recommended to use them reasonably under the guidance of doctors and avoid self-medication. If the treatment of bone tuberculosis is not timely, the condition will be easy to develop seriously or the condition will be easy to recur, it is recommended to standardize the treatment under the guidance of the doctor, and regular review.