Regarding which antihypertensive drug is more effective when combined with valsartan, it needs to be combined with the specific situation of the patient: First, if it is a young hypertensive patient, it can be combined with valsartan plus bisoprolol treatment, because young people with high blood pressure are caused by excessive excitation of the sympathetic nervous system, and valsartan has the effect of inhibiting renin and angiotensin, and bisoprolol has the effect of inhibiting sympathetic excitation. Elderly patients with hypertension, can be combined with valsartan plus nifedipine or amlodipine, because elderly patients with hypertension have a certain degree of atherosclerosis, nifedipine or amlodipine this kind of drug, in addition to the role of lowering blood pressure, but also has to improve vascular permeability, anti-platelet aggregation, more suitable for the elderly patients; Third, if chronic nephritis or nephrotic syndrome caused by high blood pressure If the hypertension is caused by chronic nephritis or nephrotic syndrome, it can be treated with combined valsartan plus furosemide and spironolactone, the latter two drugs have diuretic effect, which is more suitable for renal hypertension.