The reason for the muscle atrophy in the thighs is to deal with the cause of the muscle atrophy. Firstly, if a patient with motor neuron disease has thigh muscle atrophy, the main treatment at this time is to give nerve-nourishing drugs, such as rat nerve growth factor, and drugs to improve circulation, such as Panax notoginseng tablets or blood circulation drugs for oral administration, and at the same time to massage the limbs, because motor neuron disease does not have a good way to deal with the cause of the disease, to symptomatic treatment is the main. Second, if the muscle atrophy is caused by muscle disease, treatment can be given hormone or immunoglobulin for treatment, also can be given vitamin B1, B12 intramuscular injection or methylcobalamin oral. Third, if thigh muscle atrophy is caused by cerebrovascular disease, if cerebral infarction or cerebral hemorrhage causes hemiplegia of the limbs, muscle wasting atrophy, the main treatment at this time is to give functional exercise of the limbs, and then strengthen the muscle massage to promote the recovery of function, to prevent wasting muscle atrophy.