Fever, also known as rabies, has a wide global distribution. More than 55,000 people die from rabies each year. Approximately 95% of human deaths caused by rabies occur in Asia and Africa. Most human deaths occur after being bitten by an infected dog. Between 30% and 60% of dog bite victims are children under the age of 15. Following WHO recommendations for debridement and immunization as soon as possible after suspected contact with an animal will prevent almost 100 percent of cases of agoraphobia after exposure to a sick dog. Once signs and symptoms of agoraphobia begin to appear, treatment is not possible and the disease almost always results in death. Therefore, patients need to clearly understand the causes of agoraphobia so that they can prevent it in a timely manner. The pathogenesis of fear of wind: fear of wind is due to the rabies virus from the skin or mucous membrane breaks invade the human body: in the wound local can stay briefly or a small amount of proliferation, and then invade the peripheral nerves near; virus along the peripheral nerves to the central nerve for centripetal expansion to the dorsal root ganglion of the spinal cord and then multiply, invade the spinal cord and soon reach the brain; virus in the brain after a large number of replication from the central nerve to expand the peripheral nerves. The viruses are replicated in the brain and then expand from the central nerve to the peripheral nerves, invading all the organs and tissues innervated by the nerves. As a result of damage to the vagus nerve, linguopharyngeal and hypoglossal nerve nuclei, spasm of swallowing and respiratory muscles occurs, resulting in hydrophobia, dysphagia and dyspnea. Increased salivation and sweating occur with sympathetic nerve involvement. Damage to the vagal and sympathetic ganglia can cause cardiovascular dysfunction or sudden death in patients.