In recent years, the incidence and mortality rate of lung cancer has jumped to the top of malignant tumors. Although the existing treatments for lung cancer, such as surgical resection, chemotherapy, radiotherapy and biological therapy have made great progress, the ultimate 5-year survival rate of lung cancer patients is still unsatisfactory, which is about 10%-20%. In-depth analysis, among them, the 5-year survival rate of early-stage lung cancer patients can reach 70%-90%, and the 5-year survival rate of late-stage lung cancer patients (IIIB and IV) is difficult. Therefore, the key to improve the treatment effect and prognosis of lung cancer still lies in the “three early stages”, i.e. early detection, early diagnosis and early treatment. In clinical work, we often encounter a scene in which a patient is apprehensively holding an imaging film, a chest X-ray or CT scan reveals an isolated nodule in the lung. Is it a benign lesion or a malignant lesion? It may be difficult to answer for a while. Therefore, how to use the available clinical and imaging data to perform relevant examinations, synthesize and summarize, make a correct diagnosis, and then adopt an effective treatment strategy is a frequent task for us. In recent years, with the popular application of low-dose spiral CT examinations, some early stage lung cancer patients showing ground glass-like lesions have been screened out. How to properly view ground glass lesions? How to screen out early-stage lung cancer from many patients who present with ground glass lesions is a more difficult problem than identifying small lung nodules. One of the manifestations of peripheral lung cancer is an isolated spherical lesion in the lung, but not all isolated spherical lesions in the lung are malignant. Early stage lung cancer, tuberculosis spheroids, inflammatory pseudotumors, malignancies, sclerosing hemangiomas, mesotheliomas, congenital pulmonary cysts, pulmonary varicose spheroids, pulmonary arteriovenous fistulas, and metastatic carcinomas that metastasize into the lung from malignant tumors elsewhere are all possible. It is difficult to diagnose intrapulmonary nodules as lung cancer, or tuberculosis spheres, or malignant pseudotumor, or other lesions solely from imaging or clinical manifestations, and more often than not, small intrapulmonary nodules are classified into two categories: benign lesions or malignant lesions, the significance of which is that benign lesions can continue to be observed, while malignant lesions need to be treated immediately to avoid delaying the disease and bringing unnecessary harm and injury to patients . In the 1960s, foreign data showed that lung cancer accounted for 28.3%, metastatic cancer for 3.5%, sarcoidosis for 58.9%, and malignant nodules for 6.6%. In 1997, Webb WR reported that 50% were benign lesions, 40% were lung cancer, and 10% were metastatic cancer. In other words, benign lesions in isolated small lung nodules have been reduced to 50%. In recent years, there are clinical estimates in China that the proportion of malignant lesions is even higher than before. In recent years, isolated glassy lesions in the lung have attracted a lot of attention because they may be early adenocarcinoma of the lung, or bronchoalveolar carcinoma, or atypical adenomatous hyperplasia, which is a precursor of lung cancer and has a relatively good prognosis. If these cases can be detected in the early stage of lung cancer, it will greatly improve the treatment outcome of lung cancer.