There are five main types of chronic nephritis, including thylakoid proliferative glomerulonephritis, IgA nephropathy, thylakoid capillary glomerulonephritis, membranous nephropathy and focal segmental glomerulosclerosis.
1. Tethered proliferative glomerulonephritis: diffuse proliferation of glomerular tethered cells and tethered stroma can be seen under light microscope.
2. IgA nephropathy: it refers to glomerular disease with IgA or IgA deposition predominantly in the glomerular mesangial area, and it is the most common primary glomerular disease nowadays.
3. Tethered capillary glomerulonephritis: it is divided into two categories: primary and secondary. It is mainly characterized by thickening of glomerular basement membrane, proliferation of thylakoid cells and increase of thylakoid matrix.
4. Membranous nephropathy: it occurs in middle-aged and old-aged people, more common in men, and the peak age of onset is 50~60 years old. Diffuse glomerular lesions can be seen under the light microscope, in the early stage, only a small number of scattered distribution of small complex redophilic particles can be seen on the epithelial side of the glomerular basement membrane; and then there are nail protrusions. The basement membrane is gradually thickened.
5. Focal segmental glomerulosclerosis: under the light microscope, the lesions are focally and segmentally distributed, manifesting as sclerosis of the affected segments (increase of the thylakoid stroma, occlusion of capillaries, adhesion of the balloon, etc.), with corresponding renal tubular atrophy and renal interstitial fibrosis.
Chronic nephritis can be seen in a variety of renal pathology types, it is recommended that patients go to the regular hospital in time, under the guidance of the doctor standardized treatment.