Propofol in long-chain fatty milk is an intravenous general anesthetic, which is one of the most widely used intravenous general anesthetics in clinical practice. It is mainly used clinically in the following four situations, i. Induction and maintenance of general anesthesia. Secondly, it is used for sedation of patients during local anesthesia. Third, sedation during auxiliary ventilation therapy in intensive care patients. IV. Use in various painless examination programs in outpatient clinics, such as painless gastroenteroscopy, painless abortion, painless bronchoscopy, etc. Propofol is contraindicated in people who are allergic to propofol and its solvents, and in people who are allergic to soy and peanuts. Common side effects include hypotension and respiratory depression, and these side effects are closely related to the dose and rate of administration of propofol, as well as to the general condition of the patient’s body and the use of other sedative and analgesic drugs before anesthesia. Elderly and frail patients and patients with severe impairment of the heart, lungs, kidneys and liver, as well as those with a history of hypovolemia and epilepsy, should also be administered with caution and at a slower rate. Patients with cardiovascular and respiratory insufficiency and hypovolemia should be corrected prior to propofol administration. Patients undergoing various painless examinations in the outpatient setting should be observed for a period of time after the examination is completed and must be confirmed to have fully recovered from general anesthesia before leaving the hospital. Because propofol has an effect on the ability to drive vehicles and operate machines, patients should not drive vehicles or operate machines for a short period of time, work in potentially dangerous environments, or go home alone unaccompanied or consume alcoholic beverages.