Fever may cause transaminase elevation, clinical fever patients with transaminase elevation, the first or need to carry out the screening of viral hepatitis, need to check the hepatitis B five, hepatitis complete set. If they are all (-), and also exclude steatohepatitis, alcoholic hepatitis and self-immune liver. In addition to the common causes of elevated aminotransferases, the causes of elevated aminotransferases can be categorized as fever-induced, as fevers can be divided into two main categories: infectious and non-infectious. The common causes of infectious are bacterial or viral, while non-infectious are seen in hematologic, rheumatologic-immunologic, or neoplastic diseases. If these diseases are severe, liver function can also be impaired, in which case transaminases can be elevated. Therefore, we should actively treat the primary cause of the disease while carrying out liver-protecting treatment.