The skull is one of the more important groups of skeletal tissues that play an important role in the smooth functioning of the entire organism. However, nowadays, there are many accidents and common craniosynostosis, which can easily lead to cranial defects. Once a cranial defect occurs, the damage it can bring is far from being underestimated. First, the aesthetic aspect. The visible effect of cranial defect is that the patient’s appearance is no longer beautiful, and the patient will become very low self-esteem and psychological pressure in the long run; second, safety. Skull is the protective shield of the brain, without the protection of the skull, when impacted by external forces, it will directly injure the brain tissue and even lead to death; third, skull defect will also cause a series of uncomfortable symptoms, that is, skull defect syndrome. This can be manifested as headache, dizziness, numbness and weakness of limbs, emotional instability, and in severe cases, epilepsy may be induced. From all these, it can be seen that cranial defects should be taken seriously and it is important to have cranial repair surgery in time. Is it necessary to go to a provincial hospital for skull repair? There are specialties in the field of surgery, sometimes the provincial hospitals may not be good at skull repair, so it is recommended that patients go to a good hospital with more expertise to have their surgery done by experienced specialist doctors, so as to better improve the safety and results of the surgery. Currently, our team uses the new PEEK material for skull repair surgery and has achieved good clinical results. We have also innovatively incorporated the concept of aesthetic plastic surgery into our procedures, and have performed comprehensive PEEK skull repair plastic surgery, which better restores the anatomy of the skull and has a more natural and beautiful appearance.