The longest period of time that azithromycin can be used in a row is, generally speaking, five days. Azithromycin is a macrolide antibiotic, and this antibiotic, because of its lipid-soluble activity, is particularly likely to bind to body fat after it enters the body, thus having some accumulation in the fat. Therefore, in the instructions of azithromycin often see eat three days, stop two days, or eat five days, stop three days after taking, so the longest time to take azithromycin will not exceed five days. This is mainly related to the activity of the drug and its pharmacological properties. Azithromycin, as a macrolide antibiotic, can cover common pathogenic microorganisms in the respiratory tract, and in addition has good antibacterial activity against atypical pathogens, such as Mycoplasma, Chlamydia, Legionella, etc. It is also a very widely used antibiotic in clinical practice.