Headache and body fever are very common in clinical practice and are caused by infectious causes, mostly due to cold and fever. If the patient has no other discomfort such as coughing, coughing phlegm, peripheral muscle aches and pains, it is recommended that the patient can take oral antipyretic and analgesic drugs to relieve the symptoms, such as acetaminophen, ibuprofen extended-release capsules are commonly used clinically to relieve the patient’s symptoms. At the same time, if the patient combined with unfavorable movement of the limbs, epileptic convulsions or impaired consciousness should be suspected of intracranial infection caused by headache fever combined with fever on the body, must promptly visit the hospital to do the relevant examination, may need to extract cerebrospinal fluid to clarify the condition and actively carry out treatment.