The purpose of routine laboratory examination for renal cell carcinoma is to understand the general condition of patients and whether they are suitable for corresponding treatment measures. It mainly includes urinary routine, blood routine, erythrocyte sedimentation rate, blood glucose, blood calcium, renal function (blood urea nitrogen, blood creatinine and glomerular filtration rate), liver function, lactate dehydrogenase, alkaline phosphatase and other items. If invasive testing or surgical treatment is required, the necessary coagulation tests should be performed. The results of the above items may be manifested as hematuria, erythrocytosis, anemia, increased erythrocyte sedimentation rate, hyperglycemia, hypercalcemia, abnormal renal function and abnormal liver function in patients with renal cell carcinoma. For patients with renal tumors adjacent to or involving the renal pelvis, urine cytology examination is also required. Patients with renal tumors in isolated kidneys, bilateral renal tumors, abnormal renal function indicators and the presence of diseases that impair renal function (such as diabetes mellitus, chronic pyelonephritis, polycystic kidney, contralateral renal stone, etc.) need to undergo nuclear nephrography to understand renal function and to assess the grade of renal insufficiency. Currently, there is no recognized serum tumor marker for the early adjuvant diagnosis of renal cell carcinoma.