Thrombocytopenia nosebleeds should be treated according to the cause of thrombocytopenia. There are many causes of thrombocytopenia, the common ones are aplastic anemia, thrombotic thrombocytopenic purpura, immune thrombocytopenia, leukemia or hypersplenism. 1. Aplastic anemia: when the symptoms are mild, it can be treated with hemostatic drugs such as phenol sulfonyl ethylamine or antifibrinolytic drugs such as aminocaproic acid, etc., and at the same time, it should be treated with cyclosporine and other drugs for the cause of the disease, and hematopoietic stem cell transplantation can be carried out for the severe cases. 2. Thrombotic thrombocytopenic purpura: plasma exchange is the main treatment, followed by fresh plasma transfusion and medication, including glucocorticosteroids such as prednisone, dexamethasone, etc., and immunosuppressants such as vincristine. Splenectomy may be considered in cases of poor plasma replacement or recurrence. 3. Immune thrombocytopenia: treatment mainly involves the use of glucocorticoids and gammaglobulin. 4. Leukemia: timely chemotherapy with drugs such as cytarabine and erythromycin is needed. 5. Hypersplenism: hypersplenism will phagocytosis of normal blood cells resulting in a decrease in red blood cells, white blood cells and platelets, should first treat the primary disease, if the effect is not obvious, and splenomegaly has obvious compression symptoms, splenectomy can be considered. Thrombocytopenia nosebleed may also have other causes, should go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor standardized treatment. The above drugs should be used under the guidance of a doctor, avoid self-medication.