Cranial repair is a routine neurosurgical procedure, a common surgical procedure to repair the defective area of the skull using certain artificial materials for various reasons. Although it is a common, routine procedure, it is also a complex and systematic treatment. Patients may have many questions surrounding cranial repair. Some people ask if it is still possible to repair the skull if the skull is infected. In response to this question, it is not uncommon for patients with cranial defects to have infections in the skull itself; it is not uncommon for the scalp to become infected. If the scalp is infected, anti-infection treatment is needed, and the skull can be repaired normally after healing. If an infection of the skull itself develops into osteomyelitis of the skull, thorough surgical debridement and removal of dead bone, combined with the use of bacterially sensitive antibiotics, is the current effective treatment, with the possibility of further expansion of the bone window. After curing the infection, the skull can still be repaired normally. Regarding the skull repair, there is another common infection situation is that the titanium mesh cranial bone repair after the infection, which is not uncommon in the clinic, which also needs timely anti-infection treatment; if it is very serious and the anti-infection treatment can not be controlled well, it is very likely to need to surgically remove the titanium mesh, and wait for the infection to be cured, and then repair after the scalp grows back well. In fact, in addition to the possibility of infection, titanium mesh repair of the skull after surgery, scalp ulceration, material exposure, material collapse and deformation, sensitivity to hot and cold environments, affecting the CT, MRI and other problems. Therefore, the use of titanium mesh material for skull repair is not recommended at present. Now there is a new type of cranial bone repair material with excellent performance – polyether ether ketone PEEK, which is a kind of special polymer material, all the properties are comparable to the autologous cranium, and it has become a new trend of cranial bone repair material, which can well avoid the above problems, and it is not easy to get infected after the operation. At present, our clinic widely used polyether ether ketone PEEK as cranial bone repair material, and constantly improve and upgrade the technology and optimize the design of the material, but also innovative introduction of the concept of cosmetic plastic surgery, so as to carry out a comprehensive PEEK cranial bone repair and plastic surgery, which can achieve the structural restoration, anatomical integrity, functional perfection, beautiful appearance of the organic unity, widely acclaimed.