Cranial defect is a common disorder in neurosurgery clinic, many accidents in life may cause damage to the skull. Like traffic accidents, production safety accidents, falling from height, throwing objects from height, fighting, etc. may cause craniocerebral injury, cranial defects, as well as some of its own craniocerebral diseases such as cerebral hemorrhage, brain tumors, etc. require craniotomy treatment can not be instantly returned to the flap of the bone and the remaining cranial bone defects. So what do these patients with cranial defects need to pay attention to? This question is relatively broad, patients with cranial defects need to pay attention to a lot of places, here briefly say a few points, not necessarily comprehensive. First of all, patients should pay attention to their daily life, try to avoid strenuous exercise, especially to avoid the defective parts of the outside world by the impact of the bump, which is easy to injure the brain tissue; Secondly, patients need to pay attention to their diet, should ensure adequate nutrition, and at the same time, light diet, to avoid too much grease; There is also, to pay attention to the psychological attention to patients with cranial defects and channeling, cranial defects patients are very prone to have inferiority complexes or even depressed emotions. Patients with cranial defects are prone to low self-esteem and even depression, and their family members should communicate with the patients more often and provide professional psychological counseling when necessary; finally, the most important point is to carry out cranial repair in time. Cranial bone repair is a routine surgery in neurosurgery, the technology is very mature, but to really do a good job, it is not simple, you need to choose a good repair material, but also need to senior, experienced neurosurgeons to complete. Let’s talk about the material first, at present, most of the general hospitals in clinical use of cranial bone repair material is mainly titanium mesh, and this metal material also has some defects and shortcomings. For example, the clinical use of titanium mesh cranial bone repair may be infected with postoperative rejection, wear and tear of the scalp, material exposure, collapse and deformation, fear of cold and heat, affecting the CT resonance examination, molding effect is not ideal and so on. At present, there is a more excellent performance of the new material – polyether ether ketone PEEK material, this material in the hardness, strength, elasticity, thermal insulation, stability, histocompatibility, radiation transmissibility, plasticity and so on are comparable to the autologous skull, can be achieved ideal cranial bone repair effect. Besides, although cranial bone repair surgery is a routine surgery, it is also a great test of physician’s skills, requiring the operator to be very familiar with the anatomical structure of the head and face, and need very fine operation to achieve a good reset and protection of various tissues such as nerves, blood vessels, muscles and other tissues, and requiring the operator to have a strong psychological quality and resilience, and to properly deal with all kinds of situations that may occur during the operation, etc. At present, our team has been working with a number of surgeons in the field of cranial bone repair. Currently, our team is specialized in cranial bone repair. The team applies advanced polyether ether ketone PEEK as the cranial bone repair material, and constantly carries on the technical improvement and material optimization design, at present has 4 technical innovations, and innovatively introduces the concept of cosmetic plastic surgery, so as to carry out the comprehensive PEEK cranial bone repair and plastic surgery, which can achieve the anatomical integrity, perfect function, and beautiful organic unity of the appearance.