Today, I saw some parents in the forum say that after taking antibiotics for a long time, the frequency of colds of their children has worsened, and some babies have diarrhea, my mind also began to worry a little, because my baby has just begun to receive treatment, and there will be a long time in the future to deal with these antibiotics, but in order to cure the child’s illness, oral antibiotics and can not be avoided, what to do? Then let’s try to minimize the harm. I deliberately go online to find out about the “antibiotic” explanation and its role and side effects, the results are as follows: 1, Nouns: Antibiotics (antibiotics) is produced by microorganisms (including bacteria, fungi, actinomycetes) or higher plants and animals in the course of their lives with antipathogens or other active class of secondary metabolites, which can interfere with other living organisms, and can also interfere with other living organisms. Secondary metabolites, chemical substances that can interfere with the developmental functions of other living cells. Antibiotics commonly used in clinical practice include extracts from microbial cultures and chemically synthesized or semi-synthesized compounds. At present, no less than 10,000 kinds of natural antibiotics are known.2. Usage: Antibiotics used to be called antimicrobials, in fact, it not only kills bacteria but also has a good inhibition and killing effect on other disease-causing microorganisms such as molds, mycoplasma, chlamydia and so on, and in recent years antibiotics are usually renamed antimicrobials as antibiotics. Antibiotics can be certain microbial growth and reproduction process of a substance, antibiotics used to treat disease in addition to the direct extraction; there are completely synthetic or partially synthetic. Commonly speaking, antibiotics are used to treat a variety of bacterial infections or inhibit disease-causing microbial infections of drugs. 3, toxic reactions: ① neurological toxic reactions; aminoglycosides damage to the eighth on the brain nerve, causing tinnitus, dizziness, deafness; large doses of penicillin G or semi-synthetic penicillin or cause neuromuscular block, manifested as respiratory depression and even respiratory arrest. Chloramphenicol, cycloserine cause psychotic reactions, etc.. ② hematopoietic system toxic reactions; chloramphenicol can cause recalcitrant anemia; chloramphenicol, ampicillin, streptomycin, neomycin, etc. can sometimes cause granulocyte deficiency. Gentamicin, kanamycin, vanguardin Ⅳ, Ⅴ, Ⅵ can cause leukopenia, cephalosporins occasionally lead to erythrocytes or leukocytes, thrombocytopenia, eosinophils increase. Hepatotoxicity and nephrotoxicity: Tobramycin can occasionally cause transaminase elevation, most cephalosporins can cause transaminase, alkaline phospholipase Ⅰ and Ⅱ in high doses, polymyxins, aminoglycosides and sulfonamides can cause renal tubular damage. Gastrointestinal reactions: oral antibiotics can cause gastric discomfort, such as nausea, vomiting, epigastric fullness and loss of appetite. Among tetracyclines, gentamycin, doxycycline and dimethyltetracycline are particularly significant. Among macrolides, erythromycin is the heaviest, while madicillin and spiramycin are less severe. Tetracyclines and rifampicin can occasionally cause gastric ulcers. ⑤ Long-term use of antibiotics can lead to the wrong killing of the normal probiotic flora in the body, resulting in intestinal dysbiosis, thus causing a variety of intestinal function abnormalities and adverse reactions. Jin Shuangqi (Lactobacillus bifidus triphala tablets) can be used to replenish the normal probiotic flora in the body which is mistakenly killed by antibiotics, so as to avoid many kinds of intestinal function abnormalities and adverse reactions caused by intestinal disorders due to taking antibiotics. (6) Antibiotics can cause dysbiosis and vitamin B and K deficiencies; they can also cause secondary infections, such as pseudomembranous enteritis, acute hemorrhagic enteritis, and Candida infections. Pseudomembranous enteritis caused by lincomycin and clindamycin is the most common, followed by vancomycin IV and V. Acute hemorrhagic enteritis is mainly caused by semi-synthetic penicillin, with ampicillin causing the most chances. In addition, long-term oral administration of large doses of neomycin and the application of kanamycin cause degenerative changes in the intestinal mucosa, leading to malabsorption syndrome, so that the infant diarrhea and long-term weight gain should be pre-emphasized. A small number of people with antibiotics caused anal itching and perianal erosion, the symptoms can disappear after stopping the drug. (7) Allergic reactions to antibiotics are generally categorized as anaphylaxis, serum sickness type reaction, drug fever, rash, angioneurotic edema and anaphylactic myocardial damage. (8) Antibiotic after-effects refers to the after-effects of biological effects after discontinuation of the drug, such as permanent deafness caused by streptozotocin. Many chemotherapeutic drugs can cause “three causes” effect. Rifampicin has a teratogenicity rate of 4.3%, and chloramphenicol, gray flavomycin and certain antitumor antibiotics have mutagenic and carcinogenic effects. After the use of antibiotics, it is best to supplement probiotics after the use of antibiotics in children, the impact on the gastrointestinal tract is greater. Because under normal circumstances the human intestinal tract is parasitized with many kinds of bacteria, composed of normal flora. Normal flora in 90% is resident bacteria, mainly Escherichia coli, bifidobacteria, etc.; 10% is passing bacteria, including E. paracolonica, E. metapneumoniae, Pseudomonas aeruginosa and staphylococcus, and so on. Beneficial and harmful bacteria in the intestinal tract are mutually restrained and coordinate with each other to maintain micro-ecological balance, but also to block the invasion of foreign bacteria, thus maintaining the health of the body. However, antibiotics do not grow eyes like people, and often kill good and bad when sterilizing. As the sensitive bacteria in the normal flora are inhibited or killed, drug-resistant bacteria, such as staphylococcus, lose the resistance and constraints of other bacteria, taking advantage of the opportunity to multiply, resulting in intestinal bacterial group disorders. The child also appears to have a loss of appetite, decreased immunity and other symptoms. Infant experts specially remind parents not to panic when their children have the above symptoms, but to take probiotic supplementation to regulate their children’s intestinal flora and restore the ecological balance of intestinal flora. In order to enhance the child’s immunity, so that the impact of antibiotics on the child to reduce some, I am prepared to give the baby in the period of time to eat children’s protein powder and probiotics, I hope to play a role in this can also make the therapeutic effect faster and better, the child is sick (colds, etc.) will make the adenoids enlarged, so that the original effect of the discount, affecting the process of healing, so mothers can also try. May the children be healthy soon!