When a newborn baby’s eye boogers apply erythromycin more and more, the use of erythromycin should be stopped immediately, the eyes should be cleansed with water, and the eyes should be treated in the ophthalmology department of the regular hospital in time. The skin barrier function of the eye surface of newborn babies is weak, so in the event of bacterial infection, it is easy to cause conjunctival inflammation and redness and swelling around the eyes, but also lead to a significant increase in the secretion of eye boogers. When the eye discharge increases but erythromycin is not effective, the use of erythromycin ointment should be stopped immediately to avoid aggravation of the irritation symptoms. At the same time in the eyes of local secretion is more, use saline or water to wash the skin around the eyes, can effectively remove the secretion, and to ensure that the surrounding skin is dry and clean, parents should also take the baby to the hospital as soon as possible. Newborn babies should go to the hospital in time to determine the cause of the eye discharge, and choose the appropriate medication under the guidance of the doctor for treatment.