A patient who had surgery on the blood vessels of the lower leg showed signs of infection in the post-operative suture wound, and was later given fluids and medication in the hospital, but the infection tended to worsen progressively and pus continued to leak out. Why did this happen? One of the reasons was high blood sugar. This patient was a patient with a history of diabetes for more than 10 years. Diabetes itself is characterized by difficult wound healing, and the patient had a long history of disease and lesions in the lower extremities, which resulted in insufficient blood supply to the blood vessels, all of which could affect wound healing. There are really many cases of wound non-healing after various surgeries for diabetic patients, but summarizing the reasons, high blood sugar is just one of the factors, in addition to the following: a, foreign bodies or threads in the wound, the need to promptly clean these foreign bodies to remove the wound threads, clean up after using saline rinse the wound, iodine volt sterilization can be, good wound protection, adhere to the change of medication. Second, nutrition, diet, must pay attention to the regulation of daily diet, more food containing protein, glucose, vitamins, zinc-rich food, these foods are still very helpful for wound healing. Third, wound inflammation or wound infection caused by post-surgical wound does not heal, it is recommended that patients first do a good job of wound cleaning, cleaning, coated with iodophor, hydrogen peroxide for disinfection, selective change of medication for wound inflammation, and at the same time can be combined with some oral anti-inflammatory drugs. Fourth, due to age or fat liquefaction and other reasons caused by the post-surgical wound does not heal, this situation is more complex, to find a professional doctor for treatment, timely debridement, and use drugs to promote wound healing, pulling poison and muscle, to accelerate healing. At the same time, change the medication at the same time do a good job of wound care. The above are the main causes and treatment methods of non-healing wounds after surgery. It should be noted that diabetic patients have a particularly high risk of difficult wound healing, so it is recommended to go to a specialist or hospital specializing in the treatment of chronic difficult-to-heal wounds to avoid aggravating the wound with wrong treatment and causing irreparable damage.