Oral acyclovir, valacyclovir or ganciclovir is generally recommended for herpes in the mouth. Alternatively, oral ribavirin can be taken. Also, topical application of 3% acyclovir ointment or phthalidone ointment is an option that can promote healing of the lesions in the mouth. Physical therapy, such as ultraviolet radiation or infrared or ultra-short wave irradiation, can also be used to help relieve pain. For more severe pain, analgesic medications such as salicylates are recommended. If you have severe nerve pain, you can choose to use vitamin B12 or vitamin B1 to help nourish the nerves. It is recommended to improve the body resistance, such as using transfer factor, or thymidine to improve the immunity. Mucosal lesions in the mouth can generally be gargled with potassium permanganate solution, chlorhexidine, etc., to facilitate wound healing.