The best time to check for breast enlargement is 5-7 days after the end of menstruation, because at this time estrogen has the least effect on breast tissue, breast tissue is in a relatively quiescent state, and abnormalities and lesions of breast enlargement are most easily detected. Breast disease has its own peculiarities and the timing of the examination is closely related to the menstrual cycle. During different periods of the menstrual cycle, the breast will undergo some physiological changes of hyperplasia and rejuvenation under the influence of various related endocrine hormones, while before menstruation the estrogen level is higher, the proliferation of glandular tissue of the breast will be more obvious, the breast tissue will appear different degrees of congestion and edema, the whole breast will be thicker, some examinations will be inappropriate and will affect the judgment of the nature of the room lumps. If a mammogram is needed, it will be more painful to clip.