What is the ratio of potassium permanganate solution to water mainly depends on what the purpose is, if you use potassium permanganate solution for sitz bath, the ratio of potassium permanganate to water is about 1:5000, and if you need a high concentration of potassium permanganate solution to make wet compresses on localized wounds, the ratio is about 1:2000, which is explained as follows. 1. The ratio is about 1:5000: For patients with inflammation in the anus or perineum, sitz baths with potassium permanganate solution in the ratio of 1:5000 can keep the wounds dry and promote the recovery of the wounds, and the effect is more satisfactory. 2. Ratio of 1:2000: For patients with local skin trauma, ulcers, abscesses, etc., the concentration of potassium permanganate solution with a higher concentration of 1:2000 is commonly used for local wet compresses, which can have the effect of sterilizing the skin. In addition, there are some other preparation ratios of potassium permanganate. Patients need to formulate the concentration according to the purpose and use, and make sure to consult a doctor before use to prevent unnecessary injuries.