Isotretinoin gel is a topical drug, the general drug is used for the treatment of acne, in the use of the need to pay attention to, for the majority of patients need to be used for 6-8 weeks to see clinical efficacy. Retinoic acid gel can mainly inhibit sebaceous glands, can reduce the production of sebum, topical use of retinoic acid, sebaceous gland production can be reduced by more than 30%, can reduce the caliber of the hair follicle, reduce the follicle cavity. It can also reduce the connection between the cells of the stratum corneum and prevent hyperkeratosis of the epithelium, so it is mainly used in the clinic for the treatment of acne vulgaris. Isotretinoin Gel is used for the treatment of acne, patients should not be too anxious in the initial use of the drug, and should use the drug according to the course of treatment. During the use of the drug must be in accordance with the recommended usage and dosage, the drug is usually used 1-2 times a day, take a small amount of it to apply to the affected area, you need to wash the skin before using the drug, and the skin to be applied to the area of dryness before using the drug. When used in accordance with the course of use, usually need to use 6-8 weeks to see clinical results. Isotretinoin Gel may cause a burning sensation or mild to moderate irritation, redness or peeling when the medication is started, and these reactions may disappear when the medication is discontinued. If irritation persists and is severe, discontinue use and consult your doctor. The exposed area where it is applied should be protected from sunlight and UV rays, or if exposure is unavoidable, sunscreen medication should be applied or shading measures should be taken.