Three major misconceptions in the diagnosis and treatment of dwarfism

  Myth 1: Don’t treat dwarfism as late growth A common problem in the diagnosis of growth hormone deficiency dwarfism is that parents often fail to notice the slowed growth rate of their children in time, and often wait until their children are significantly behind in height before paying attention. In addition, it has been found that many parents often take “short” as “late growth” and imagine that their children will have an unexpected period of rapid growth during adolescence, but as a result, the best time to diagnose and treat short is missed. Therefore, clinicians and health care workers should assist parents to regularly check the height, calculate the growth rate, and closely observe the growth curve of the affected children.  Early identification of the cause and early standardized treatment can avoid missing the good opportunity for growth. The earlier a child with GHD is identified, not only is hGH treatment more effective, but also saves money. In addition, for some patients, growth retardation or decreased growth rate may be the early clinical manifestation of intracranial tumor, so for these patients, cranial MRI examination should be performed as much as possible to avoid missing the diagnosis and delaying the treatment. If parents find that their children are shorter than their peers, they should seek medical advice in time to avoid delaying the best treatment for their children.  In our long-term clinical practice, we often come across some parents and children who are in a hurry to seek medical help. With the improvement of the standard of living, the average height of adolescents around us is also gradually rising, parents and social expectations of children’s height is “high”, we seem to have entered an “era of fear of short”, many boys hope that they are like Yao Ming Many boys want to be as tall and graceful as Yao Ming, while girls are equally eager to be as tall and graceful as models.  However, there are objective rules for a person’s height. If the parents themselves are not tall, but they want their children to grow up to 5’8″, or if it is clear that the epiphysis is closed and can no longer grow, they still do not give up. The use of some extreme means of height increase, such as broken bone height increase surgery, once the broken bone height increase surgery may be infected, or even cause osteomyelitis, resulting in disability.  After the surgery, it causes artificial unequal length of legs. Here we would like to remind those people who expect to achieve perfect height by cosmetic bone breaking: Be cautious, a healthy and sound body is far more important than getting rid of a slightly less-than-ideal height.  Myth 3: Growth hormone therapy is not a panacea Research on the etiological composition of dwarfism shows that dwarfism caused by genetic factors and delayed youth development accounts for about 2/3, while pathological dwarfism including idiopathic dwarfism, growth hormone deficiency, precocious puberty, bone development disorder, chromosomal abnormalities, intrauterine growth retardation, Turner syndrome, etc. only accounts for 1/3, and it should also be noted that some of the causes are intracranial, especially hypothalamic or pituitary tumors.  Therefore, in the diagnosis of dwarfism, the first thing is to clarify the etiology. If growth hormone is used to treat patients with dwarfism due to intracranial tumors, the consequences will be serious. Therefore, it is necessary to do head MRI for judgment before intervention treatment with growth hormone. At the same time, if we are satisfied with growth hormone treatment, but ignore the comprehensive treatment such as balanced diet, exercise, quality sleep and proper psychological adjustment, the effect of growth hormone treatment will definitely be affected, which will eventually cause unnecessary economic waste.