The more common causes of rib bone destruction are bone tumor, tuberculosis, osteoporosis, osteomyelitis, etc. It is necessary to improve the auxiliary examination in order to clarify the etiology. 1. Bone tumor: most of them are malignant tumors, which can be primary malignant tumor of ribs or malignant tumors in other parts of the body with metastasis to ribs, for example, lung cancer is more common. 2. Tuberculosis: caused by rib tuberculosis, mainly due to tuberculosis mycobacteria invasion of the ribs, patients mostly have low fever, fatigue, night sweating (abnormal sweating after going to sleep, and the sweating stops after waking up) and other systemic manifestations. 3. Osteoporosis: mostly seen in the elderly, it is related to many factors, mainly with calcium absorption disorder, hormone metabolism disorders, bone metabolism regulation abnormality and so on. 4. Osteomyelitis: it is the infection of bone marrow caused by bacteria invading through blood and nearby infected foci, and it can also lead to the destruction of rib bone, which is often accompanied by fever, chills and other systemic manifestations. It is recommended to go to the hospital for examination in order to clarify the cause of the disease.