Vulvar leukoplakia is a dark red, white patch of skin on the vulva. Vulvar leukoplakia mainly occurs in the labia majora, between labia majora and labia minora, clitoris and other parts of the vulva. Early on, the skin appears dark red or pink, and then becomes white after over-keratinization, and as the skin thickens and increases in pigmentation, it will develop mossy changes. Patients may also suffer from itching of the vulva, and excessive scratching may cause localized thickening and roughness of the skin. Vulvar leukoplakia will have skin breakage after excessive scratching, which will lead to infection, and the patient will have painful manifestations. At the same time, the epidermal atrophy and hyperkeratosis will reduce melanin, which will lead to pale and wrinkled vulva. After the appearance of vulvar leukoplakia, it is necessary to go to the regular hospital for medical treatment in time to avoid delaying the condition.