Cranial defects are relatively common in life and people are not unfamiliar with them. According to the survey, there are many reasons for cranial defects, such as craniocerebral trauma, brain surgery to remove the bone flap, tumor resection, chronic osteomyelitis of the skull, etc. So what should patients do about the cranial defects caused by brain tumors after open-heart treatment? After the cranial defect, the right thing for patients should be to see whether the defect area reaches the range of values specified by the surgery, and then seek regular hospitals to repair the defect 2-3 months after the defect, so that their skull can be restored as before. After the cranial defect, the patient’s brain tissue loses its strong protection and is exposed to atmospheric pressure, which will directly affect the normal functioning of the tissues in the brain, and it will also cause the patient to have a strong sense of inferiority due to the unsightly appearance, reduce normal communication with others, and lead to a decline in the quality of life cure. It may also cause dizziness, headache and other adverse reactions. To summarize, patients should be repaired as soon as possible after the occurrence of cranial defects. Through cranial bone repair, the patient’s defective area can be restored as before, and the person will become more and more self-confident, and do not need to worry about the safety at any time when going out. Currently, the common repair materials include traditional titanium mesh and advanced peek material, but titanium mesh has been clinically tested and found to have some problems, such as postoperative abrasion or cutting damage to the scalp, affecting a variety of imaging tests, and may also lead to xenophobia or infection. peek material is different, and its performance is very close to that of the human skull, which not only overcomes many drawbacks of titanium mesh, but also provides a better solution after the operation. It not only overcomes the many disadvantages of titanium mesh, but also realizes the symmetry of the two sides of the skull after the operation, with a natural and beautiful appearance. If conditions permit, it is recommended that patients undergo peek cranioplasty.