Hand pain when touching cold water may be related to hand trauma, arthritis, Raynaud’s syndrome and other diseases, according to the cause of the general treatment and drug therapy. 1. Hand trauma: it can be seen in cuts and lacerations of the hand, etc. When the wound touches cold water, it can produce neuralgia, at this time, it can be prevented from infection by protecting the local skin, using iodophor and alcohol as prescribed by the doctor, and avoiding touching cold water again. 2. Arthritis: common in rheumatoid arthritis and gouty arthritis, cold stimulation is often the main triggering factor, and may be accompanied by local redness and swelling, etc., can be avoided by avoiding contact with cold water, and at the same time, with non-steroidal anti-inflammatory drugs such as ibuprofen and other medications for symptomatic pain relief treatment. 3. Raynaud’s syndrome: it is caused by paroxysmal spasm of small arteries, which may appear localized pale and cold, bruising, pain and other symptoms, cold and emotional excitement can be triggered, nifedipine, perphenazine and other drugs, and pay attention to keep warm. In addition, it should also pay attention to other causes of the above symptoms, it is recommended to seek timely medical treatment to avoid delaying the condition.