Duodenal adenomas are mostly solitary, single with tibial adenomas that are prone to pyloric obstruction, and multiple adenomas are rare. There are endoscopic resection and surgical resection within the treatment modalities of duodenal adenoma, endoscopic resection treatment has high recurrence rate, and surgical resection is the main treatment modality. 1. Endoscopic resection: it refers to resecting the tumor under endoscopy, which is suitable for those whose tumors are relatively small in size and confined to the mucosa and submucosa. It has the advantages of small trauma and no need of anesthesia, but the disadvantage is high recurrence rate. 2. Surgical resection: direct incision of duodenum to remove the tumor, which is the first choice of duodenal adenoma treatment. This method of resection is more thorough, with less chance of recurrence, especially suitable for patients with large tumors. After the operation, we need to pay attention to observe the changes of the condition. Early to be fasting water, such as treatment, the anus appeared gas defecation before you can start to eat fluids. If there are symptoms related to duodenal adenoma, it is recommended to consult a doctor in time and treat it actively to avoid the risk of cancer and metastasis.