Edema at the end of dialysis in nephropathy may be due to dialysis insufficiency, hypoproteinemia, drug effects and so on. 1. Inadequate dialysis: excessive weight gain before dialysis, the amount of dehydration involved in dialysis is not enough to reach the dry weight, edema can occur; secondly, the normal setting of dialysis parameters, when the patient has low blood pressure during dialysis and other reasons, it is necessary to end dialysis in advance, resulting in a reduction in the amount of ultrafiltration, which leads to the occurrence of edema. 2. Hypoproteinemia: patients with renal disease have deviation of digestive tract reaction and nutrient absorption, low blood albumin, and after dialysis, it can lead to even lower blood albumin, and if albumin is not replenished in time, edema is easy to occur. 3. Drug effects: some drugs (such as nifedipine), long-term use can appear angioedema and other conditions, according to the situation need to consider adjusting the treatment program. If there is still edema after dialysis, it is recommended that the patient should go to the hospital in time, improve the examination under the guidance of the doctor, clarify the cause of the disease, and adjust the treatment plan in time to avoid delaying the condition.