Female macrosomia is characterized by an enlarged clitoris in infancy, which grows to resemble a boy’s penis, and a labia majora that resemble a boy’s scrotum but without testicles. Female macropubic patients, premature appearance of pubic hair, and skin acne, body development is too fast, the length of the body over the same age of children, epiphyseal growth is also far beyond the age, if you can not find out the cause of the disease, epiphysis will be fused prematurely, to the adult height than the same age of the people to be shorter. The clitoris can be enlarged in female infancy, and with the growth of the body in the later stage, it gradually increases like a boy’s penis, and the labia majora resemble a boy’s scrotum but without testicles. Macrognathia is one of the clinical manifestations of congenital adrenal hyperplasia, which is mainly due to defects in certain enzymes necessary for the synthesis of adrenocorticotropic hormone, resulting in a failure to synthesize the hormone normally.