How can you quickly determine the clinical significance of a tumor marker when you see it on a checklist? Let this chart tell you. In addition to malignant tumors, other factors that cause elevated tumor markers include: 1, benign diseases, such as inflammatory diseases: AFP, CA19-9, CEA will be elevated in benign liver diseases; β2-microglobulin and CA15-3, CA19-9, CEA and PSA will be elevated in renal failure; CA19-9 concentration can be increased in rheumatic diseases; 2, physiological changes: pregnancy AFP, CA125, HCG will be elevated; 3, bad habits: smoking, alcoholism; 4, caused by the examination: after repeated rectal fingerprinting, PSA value can be elevated; 5, taking certain drugs; 6, keeping pets; In addition, the contamination of the blood sampling process, the rupture of the red blood cells caused by the blood sampling, the specimen is not properly preserved, the difference between the reagents and the detection of non-standardized and other factors will also interfere with the results of the examination. Can elevated tumor markers clarify which part of the body has the tumor? Sometimes it is possible, but in most cases it cannot be determined by tumor markers alone and needs to be combined with other tests. One tumor marker is often associated with multiple malignant tumors. The following are some common tumor markers and the organs they suggest may have tumors: 1. CA19-9 pancreas; gastrointestinal tract and liver and gallbladder; 2. CA15-3 breast; lungs, ovary, liver; 3. CA242 colorectal, pancreas, ovary; 4. CA72-4 stomach; ovary, pancreas, breast; 5. CA125 ovary; uterus, pancreas, liver, ovary, pancreas, breast; 5. CA125 ovary; 5. CA125 pancreas; ovary; pancreas; pancreas; uterus; pancreas; pancreas; pancreas; pancreas; breast; 5. CA125 ovary. uterus, pancreas, liver, lungs; 6, CA50 pancreas, breast, lungs, gastrointestinal tract and hepatobiliary. In recent years, it has been found that PSA (prostate antigen) is also not exclusive to men, about 1/3 of female breast cancer patients are also increased, and the specificity is more than 90% Similarly, a tumor may also have a variety of tumor markers are elevated, such as pancreatic cancer patients may CA19-9, CA242, CA125, etc. are elevated at the same time. Tumor markers are normal, does it exclude the tumor? The answer is still no. Some tumors do not have elevated tumor markers from the beginning to the end, while some tumor markers are normal in the early stage and will be elevated only when the disease develops to a certain extent. There are many types of tumor markers, and many of them are still under research, so it is impossible to check all the indicators.