The normal value of alanine aminotransferase is between 0-40 U/L, with 44 suggesting a slightly higher level, which is usually not serious. However, it may also occur in liver failure and other serious liver disease damage, and it is necessary to clarify the possible factors and actively avoid or take treatment. 1. Elevation caused by physiological factors: staying up late, drinking alcohol, overeating, excessive exercise, etc. These conditions can lead to elevation of ALT, which is generally not a serious problem. The problem is usually not serious. It can be observed dynamically for the time being, and after avoiding these triggering factors, it will drop to the normal range. 2. Hepatobiliary disease elevation: due to liver cell damage, resulting in cell membrane damage, cell necrosis or rupture decomposition, alanine aminotransferase into the blood, the blood alanine aminotransferase elevation, the elevation of the obvious means that the liver cell damage is serious. It tends to be mildly elevated in chronic viral hepatitis, markedly elevated in acute viral hepatitis, and normal or mildly elevated in non-viral liver diseases such as alcoholic liver disease, substance hepatitis, fatty liver, and liver cancer. However, liver failure and other serious liver disease damage may also occur due to severe low liver function, need to clarify the possible factors, can not be fully judged by the alanine aminotransferase index alone, need to be actively examined and take treatment. It is recommended to go to the hospital immediately for examination to prevent further deterioration of the condition, and treatment under the guidance of a specialist is recommended.