Tracheoscopic drug injection has become one of the important treatments for tracheobronchial lesions. In addition to being used for malignant tumors, it is also used for benign lesions such as tuberculosis and hemorrhage. Tracheoscopic treatment of lung cancer Chemotherapy is one of the important treatment methods for lung cancer. The common methods of drug delivery are oral or intravenous systemic chemotherapy or transarterial local chemotherapy. In recent years, with the development of tracheoscopic treatment technology, microscopic drug injection has also become an important method of chemotherapy for lung cancer. The response rate of cancer cells to drugs is directly dependent on the concentration and duration of direct contact between drugs and cancer cells, in addition to factors such as drug configuration, dosage form and dose. If drugs are administered by oral or intravenous route, the drug concentration in circulating blood will reach the peak soon and the half-life will be short, and the local drug concentration in tumor will be relatively low, so it is difficult to achieve effective therapeutic effect. Trans-tracheoscopic local drug chemotherapy can significantly increase the drug concentration in the tumor site. According to different lesion sites, we adopt corresponding body position to give the drugs sufficient local action time, and choose platinum-based cycle non-specific anti-cancer and adriamycin drugs, which can act directly on DNA and thus inhibit the cancer cells that divide vigorously, and the dosage is relatively small to reduce the systemic side effects of chemotherapy drugs. Due to the high local drug concentration in tumor tissues and long duration of action, it can shrink the tumor, thus relieving the obstruction of airway, relieving dyspnea, pulmonary atelectasis and obstructive pneumonia, effectively improving ventilation, reducing the pain of advanced lung cancer patients, improving the quality of survival and prolonging life. This method has the following advantages: 1. Reliable efficacy and obvious recent curative effect, which can rapidly relieve the symptoms, especially for the lumen obstruction caused by tumor, which can make the tumor shrink as soon as possible and relieve the airway obstruction, thus obviously relieving the dyspnea, pulmonary atelectasis and obstructive pneumonia and improving the survival quality of patients. In addition to improving the survival rate, local plus systemic chemotherapy can also reduce the organ-specific and non-specific symptoms caused by lung cancer. A large number of studies have proved that transtracheal therapy can significantly improve patients’ debilitating symptoms, and the symptom reduction rate exceeds the objective response rate. 2. There are few complications, only a small amount of bleeding, which can be relieved naturally the next day. In case of excessive bleeding, epinephrine or hemostatic drugs are available. 3.Systemic side effects such as bone marrow suppression and gastrointestinal symptoms are mild, which improves the patient’s tolerance of the method. 4.The operation is simple and less dangerous. Compared with conventional tracheoscopy, it does not increase the patient’s pain more. 5.Widely applicable, it can be used for all types of endotracheal type and infiltrating type of lung cancer.