In order to prevent adverse reactions and complications of hormones and avoid blind or inappropriate use of hormones, the following points should be noted: 1. The indications and contraindications for the use of corticosteroids should be strictly mastered. In general, osteoarthritis and ankylosing spondylitis patients should not use hormones, infectious, tuberculous arthritis and tumor neck, shoulder and back pain prohibit hormones. 2, to strictly control the dose and course of treatment to reduce the adverse effects of hormones to a minimum. If the hormone dose is large and the time is long, antispasmodics, alkaline drugs and anticholinergic drugs should be used together, especially for those who have a history of peptic ulcer.3. The dose should be gradually reduced after the symptoms are controlled, and the drug should not be stopped suddenly or replaced by other drugs in the course of its treatment. Otherwise, the original symptoms will recur or worsen, and even the occurrence of adrenocortical insufficiency syndrome. 4, to start the application of hormone therapy rheumatoid arthritis, should be combined with Ryder, penicillamine or other drugs that change the course of the disease, and should be used for more than 1 year to control the development of rheumatoid arthritis, to prevent relapse after the discontinuation of hormones. 5, to prevent the spread or infection. For those who already have infection, effective antimicrobial agents must be used at the same time while applying hormone therapy; also be alert to severe mycobacterial diathesis. 6. To take a low salt or salt-free diet during hormone therapy, and regularly observe blood pressure, blood potassium, blood sugar and urine sugar. Hypokalemia should be prevented. If necessary, supplement potassium chloride. 7. To be in the long-term application of hormones in elderly boils, special attention should be paid to the phenomenon of protein catabolism and metabolism, such as osteoporosis and pathological fracture. If necessary, testosterone propionate or nandrolone phenylpropionate should be given at the same time to stop or delay the occurrence of this phenomenon. Calcium tablets and vitamin A and D pills should also be supplemented opportunistically. In conclusion, health care professionals and patients with neck, shoulder and back pain should always remember this phrase: Hormones have risks and should be used with caution!