Sodium bicarbonate flushing nasoenteric tube mainly utilizes the alkaline condition of sodium bicarbonate solution to dissolve the acidic clots blocking the nasoenteric tube, avoiding the blockage of nasoenteric tube, or unblocking the blocked nasoenteric tube. By keeping the nasoenteric tube, enteral nutrition can be provided to critically ill patients to provide the nutrition needed to maintain the body’s metabolism. However, the lumen of the nasoenteric tube is long and thin, and the enteral nutrition solution is viscous, with a slow passage speed, which is prone to precipitation in the tube, and some drugs are acidic, which can make the protein in the nutrition solution coagulate, and may also lead to the blockage of the tube lumen. Flushing the nasoenteric tube with sodium bicarbonate uses 5% sodium bicarbonate solution, which has a pH of 7.5~8.0 and is an alkaline solution that can dissolve acidic clots and can dissolve lecithin and other components to keep the tube lumen open and prevent blockage of the nasoenteric tube. When using nasoenteric tubes, they should be used in strict accordance with medical advice, and it is recommended that a doctor be consulted promptly if there are any problems with their use.