Pimples, or acne, which appear swollen and painful, are considered to be aggravated acne symptoms and require medication and general treatment. There is no quick cure for acne due to the difference in individual constitution and condition. 1. Medication: Topical retinoids such as adapalene gel, tazarotene gel, antibiotics such as fusidic acid cream, etc., combined with oral isotretinoin or viamin, doxycycline or minocycline. 2. General treatment: avoid squeezing the swollen and painful pimples with hands. Pay attention to a light diet in daily life, avoiding intake of high sugar, high fat, spicy and stimulating food. Choose the right cleanser to clean the skin daily and moisturize it well. When the above situation occurs, it is recommended that the patient consult a doctor in time for targeted treatment, so as to avoid the emergence of other undesirable symptoms. The above medications should be used under the guidance of a doctor.