The S6 segments of the liver, which are generally distinguished according to the anatomical landmarks of the liver, refer mainly to the right posterior lobe of the liver. These segments are generally based on the intrahepatic portal vein and the branches of the hepatic vein. the S6 segment is mainly the section determined by the right hepatic vein and the right branch of the portal vein, which is an important reference in clinical practice to correctly guide surgical treatment as well as the location markers of surgical disease. with lesions in the S6 segment, a complete and precise anatomical resection of the liver is required during surgery along these anatomical landmarks of the liver. Therefore, these indicators are generally used internationally to properly guide treatment and better communication.