Cranial repair is the process of surgical plastic repair of the defective portion of the skull with artificial materials following defects of various causes. Cranial repair is mainly performed on defective skulls caused by debridement and craniotomy, and usually requires a certain time interval between the formation of the skull defect and the execution of the repair surgery. Usually, the surgeon replaces the skull at the site of the defect with a different repair material. Artificial repair of the defective skull can improve the patient’s appearance, eliminate the psychological effects caused by the skull defect, and restore the physiological state of the brain tissue. Cranioplasty has been shown to improve EEG abnormalities, cerebral blood flow abnormalities and other neurological disorders. Therefore cranioplasty should be performed promptly after cranial defects. A common question many patients have is the best material for cranial bone repair. What is the best material for cranial bone repair? At present, the cranial bone repair material is a new type of peek material, PEEK material to do cranial bone repair is better than the traditional repair material, and the preoperative is based on the patient’s cranial defect shape through the 3D printing, the appearance and the previous no difference. Through clinical practice found that PEEK material low density, insensitive to temperature, have high tissue stability, so that it can be sterilized at high temperatures or radiation does not produce deformation. And through a large number of clinical feedback found that PEEK material has ray transmissibility, there will be no effect on the CT results. Warm tips: the treatment of cranial bone repair surgery is recommended to choose a regular hospital, and must listen to the doctor’s advice during treatment. In ordinary life to develop good habits, early repair, early recovery of health.